The famous story of Cleopatra’s suicide gets points for drama and crowd appeal: Her lover, Mark Antony, had been defeated in battle by Octavian and, hearing that Cleopatra had been killed, had stabbed himself in the stomach. Very much alive, after witnessing his death, the beautiful last Pharaoh of Ancient Egypt pressed a deadly asp to her breast, taking her own life as well.

But what if Cleopatra didn’t commit suicide at all?

Pat Brown, author of the new book, The Murder of Cleopatra: History’s Greatest Cold Case, argues that the “Queen of Kings” did not take her own life. Rather, she was murdered, and her perpetrators managed to spin a story that has endured for more than 2,000 years....