Columbus Carried Syphilis From New World to Europe, Study Suggests
A new analysis of the genetics of syphilis provides support for the theory that the disease hitched a ride with Christopher Columbus from the New World back to the Old World.
But in a new wrinkle, the research suggests the disease may not have been transmitted through sex until it adapted to the environment in Europe.
"It evolved this whole new transmission mode, and it didn't take very many genetic changes," said study lead author Kristin Harper, a graduate student at Emory University. "What this tells us is that new transmission modes may evolve pretty rapidly. This is important to us today, because we're worried about things like avian influenza going from human to human."
Syphilis is usually easily treated today, typically with antibiotics such as penicillin. But U.S. health officials have failed in their efforts to eliminate it; minorities and gay men have been among those most likely to be infected.
Then there's the long-running controversy over how syphilis found its way to Europe, where it spread havoc for centuries. One theory holds that the disease was already in Europe before the explorer Columbus returned, but people didn't diagnose it correctly, Harper said.
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But in a new wrinkle, the research suggests the disease may not have been transmitted through sex until it adapted to the environment in Europe.
"It evolved this whole new transmission mode, and it didn't take very many genetic changes," said study lead author Kristin Harper, a graduate student at Emory University. "What this tells us is that new transmission modes may evolve pretty rapidly. This is important to us today, because we're worried about things like avian influenza going from human to human."
Syphilis is usually easily treated today, typically with antibiotics such as penicillin. But U.S. health officials have failed in their efforts to eliminate it; minorities and gay men have been among those most likely to be infected.
Then there's the long-running controversy over how syphilis found its way to Europe, where it spread havoc for centuries. One theory holds that the disease was already in Europe before the explorer Columbus returned, but people didn't diagnose it correctly, Harper said.